External Iliac Artery Endofibrosis in Cyclists
DOI:
https://doi.org/10.28985/1526.jsc.03%20Keywords:
Bicycling, Claudication, Cyclist, Endofibrosis, Endurance Exercise, External Iliac ArteryAbstract
An underrecognized clinical condition that may afflict high level cyclists is external iliac artery endofibrosis (EIAE). EIAE is an intermittent claudication vascular condition that results from intimal narrowing most often of the external iliac artery (EIA). Symptoms are reported as thigh pain and loss of power that occur during high intensity efforts. EIAE is theorized to be a result of the mechanical and hemodynamic stress within the EIA heightened by psoas muscle hypertrophy in conjunction with the repetitive and extreme hip flexion coupled with high cardiac output. A combination of clinical tests (e.g. ankle-brachial index) in concert with imaging and vascular studies (e.g. duplex ultrasound) is necessary to arrive at an accurate diagnosis. The mean time from symptom onset to diagnosis is 3 years. Conservative interventions, which consist of bike hardware adjustments and/or posture modifications while riding, are generally not acceptable for a competitive cyclist. Surgical interventions take the form of percutaneous/endoscopic (e.g. balloon angioplasty, stent insertion) or open procedures (e.g. arterial release, endarterectomy, artery reconstruction) to restore arterial flow. Long-term outcomes following percutaneous procedures have followed a finite number of patients to date and are not recommended as a primary intervention for EIAE. Outcomes following open surgical procedures are strong with most riders being able to return to preinjury levels of competition. Greater awareness of EIAE among the scientific and medical community who work with cyclists is needed to improve the efficiency and overall management of EIAE.
Downloads
References
Abraham P, Bickert S, Viell B, Chevalier JM, Saumet JL. (2001). Pressure measurements at rest and after heavy exercise to detect moderate arterial lesions in athletes. J Vasc Surg., 33:721-727. DOI: 10.1067/mva.2001.112802
Abraham P, Chevalier JM, Loire R, Saumet JL. (1999). External iliac artery endofibrosis in a young cyclist. Circulation, 100:e38.
Alimi YS, Accrocca F, Barthelemy P, Hartung O, Dubuc M, Boufi M. (2004). Comparison between duplex scanning and angiographic findings in the evaluation of functional iliac obstruction in top endurance athletes. Eur J Vasc Endovasc Surg., 28:513-519. DOI: 10.1016/j.ejvs.2004.08.008
Barrios C, Bernardo ND, Vera P, Laiz C, Hadala M. (2015). Changes in sports injuries incidence over time in world-class road cyclists. Int J Sports Med., 36:241-248. DOI: 10.1055/s-0034-1389983
Bender MHM, Schep G, deVries WR, Hoogeveen AR, Wijn PFF. (2004). Sports-related flow limitations in the iliac arteries in endurance athletes. Sports Med., 34:427-442.
Brunelle R, Baradaran N, Keeler S. (2016). Iliac artery endofibrosis – case study of an elite triathlete. Can Fam Physician,; 62:318-320.
Chevalier JM, Enon B, Walder J, et al. (1986). Endofibrosis of the external iliac artery in bicycle racers: an unrecognized pathological state. Ann Vasc Surg., 1:297-303.
Clarsen B, Krosshaug T, Bahr R. (2010). Overuse injuries in professional road cyclists. Am J Sports Med., 38(12):2494-2501. DOI: 10.1177/0363546510376816
Dannenberg AL, Needle S, Mullady D, Kolodner KB. (1996). Predictors of injury among 1638 riders in a recreational long-distance bicycle tour: cycle across Maryland. Am J Sports Med., 24:747-753.
D’Abate F, Paraskevas KI, Oates C, Palfreeman R. Hinchliffe RJ. (2017). Angiology, 68(3):225-232. DOI: 10.1177/0003319716649113
Falor AE, Zobel M, de Virgilio C. (2013). External iliac artery fibrosis in endurance athletes successfully treated with bypass grafting. Ann Vasc Surg., 27:1183.e1-1183.e4. DOI: 10.1016/j.avsg.2013.01.012
Fernandez-Garcia BJ, Fernandez JA, Garcia FV. (2002). Diagnosing external iliac endofibrosis by postexercise ankle to arm index in cyclists. Med Sci Sports Exerc., 34:222-227.
Feugier P, Chevalier JM. (2004). Endofibrosis of the iliac arteries: an underestimated problem. Acta Chir Belg., 104:635-640.
Fisher AT, Tran K, Dossabhoy SS, Sorondo S, Fereydooni A, Lee JT. (2022). Anatomic factors contributing to external iliac artery endofibrosis in high-performance athletes. Ann Vasc Surg., 87:181-187. DOI: 10.1016/j.avsg.2022.05.011
Flors L, Leiva-Salinas C, Bozlar U, Norton PT, Cherry KJ, Housseini AM, et. al. (2011). Imaging evaluation of flow limitations in the iliac arteries in endurance athletes: diagnosis and treatment follow-up. AJR, 197:W948-W955. DOI: 10.2214/AJR.11.6547
Ford SJ, Rehman A, Bradbury AW. (2003). External iliac endofibrosis in endurance athletes: a novel case in an endurance runner and a review of the literature. Eur J Vasc Endovasc Surg., 26:629-634. DOI: 10.1016/j.ejvs.2003.08.003
Gahwiler R, Hirschmuller A, Grumann T, Issak A, Thalhammer C. (2021). Exercise induced leg pain due to endofibrosis of external iliac artery. Vasa., 50(2):92-100. DOI: 10.1024/0301-1526/a000909
Getzin AR, Silberman MR. Iliac flow limitations in endurance athletes. (2010). Curr Sports Med Rep., 9:334-337.
Giannoukas AD, Berczi V, Anoop U, Cleveland TJ, Beard JD, Gaines PA. (2006). Endofibrosis of iliac arteries in high-performance athletes: diagnostic approach and minimally invasive endovascular treatment. Cardiovasc Intervent Radiol., 29:866–869. DOI: 10.1007/s00270-004-0202-6
Hinchliffe RJ, D’Abate F. Abraham P, Alimi Y, Beard M, et al. (2016). Diagnosis and management of iliac artery endofibrosis: result of a delphi consensus study. Eur J of Vasc Endovasc Surg., 2(1):90-98. DOI: 10.1016/j.ejvs.2016.04.004
Kim H, Lee CK, Yeom JS, et. al. (2013). Asymmetry of the cross-sectional area of paravertebral and psoas muscle in patients with degenerative scoliosis. Eur Spine J., 22:1332-1338. DOI: 10.1007/s00586-013-2740-6
Kral CA, Han DC, Edwards WD, Spittell PC, Tazelaar HD, Cherry KJ. (2002). Obstructive external iliac arteriopathy in avid bicyclists: new and variable histopathologic features in four women. J Vasc Surg., 36:565-70. DOI: 10.1067/mva.2002.126558
Lim CS, Gohel MS, Shepherd AC, Davies AH. (2009). Iliac artery compression in cyclists: mechanisms, diagnosis and treatment. Eur J Vasc Endovasc Surg., 38:180-186. DOI: 10.1016/j.ejvs.2009.03.024
Lindo FA, Lee JT, Morta J, Ross E, Shub Y, Wilson C. (2019). Diagnosis and management of external iliac endofibrosis: a case report. J Vasc Nurs., 37:86-90. DOI: 10.1016/j.jvn.2018.11.008
Maree AO, Islam MA, Snuderl M, et al., (2007). External iliac artery endofibrosis in an amateur runner: hemodynamic, angiographic, histopathological evaluation and percutaneous revascularization. Vasc Med., 12:203-206. DOI: 10.1177/1358863X07080844
Martinez A, Wells BJ. (2022). Vascular disease patient information page: external iliac artery endofibrosis. Vasc Med., 27(2):207-210. DOI: 10.1177/1358863X221076565
Mazurova T, Sengul I, Toman D, et al. (2023). Endofibrosis as a cause of peripheral artery disease: a comprehensive review and proposal of two novel algorithms for diagnosis and treatment. Rev Assoc Med Bras., 69(2):352-356. DOI: 10.1590/1806-9282.20221374
Mosimann R, Walder J, VanMelle G. (1985). Stenotic intimal thickening of the external iliac artery: illness of the competition cyclists? Report of two cases. Vasc Endovascular Surg., 19:258 263. DOI: 10.1177/153857448501900411
Nayak SB, Aithal AP, Kumar N, Regunathan D, Shetty P, Maloor PA. (2019). A cadaveric study of variations of external iliac artery and its implication in trauma and radiology. Morphologie, 103:24-31. DOI: 10.1016/j.morpho.2018.10.001
Nayak SB, Kumar N, Shetty SD, Guru A. (2012). Looped external iliac artery – a case report. Int J Morphol., 30(3):870-871. DOI: 10.4067/S0717-95022012000300017
Peach G, Schep G, Palfreeman R, Beard JD, Thompson MM, Hinchliffe RJ. (2012). Endofibrosis and kinking of the iliac arteries in athletes: a systematic review. Eur J of Vasc Endovasc Surg., 43:208-217. DOI: 10.1016/j.ejvs.2011.11.019
Peake LK, D’Abate F, Farrah J, Morgan M, Hinchliffe RJ (2018). The investigation and management of iliac artery endofibrosis: lessons learned from a case series. Eur J Vasc Endovasc Surg., 55:577-583. DOI: 10.1016/j.ejvs.2018.01.018
Politano AD, Tracci MC, Gupta N, Hagspiel KD, Angle JF et al. (2012). Results of external iliac artery reconstruction in avid cyclists. J Vasc Surg. 55:1338-1345. DOI: 10.1016/j.jvs.2011.11.106
Rajasekaran S, Finnoff JT. (2016). Exertional leg pain. Phys Med Rehabil Clin N Am., 27:91-119. DOI: 10.1016/j.pmr.2015.08.012
Rousselet MC, Saint-Andre JP, L’Hoste P, Enon B, Megret A, Chevalier JM. (1990). Stenotic intimal thickening of the external iliac artery in competition cyclists. Hum Pathol., 21:524-529.
Rouviere O, Feugier P, Gutierrez JP, Chevalier JM. (2014). Arterial endofibrosis in endurance athletes: angiographic features and classification. Radiology, 273:294-303.
Scavee V, Stainier L, Deltombe T, et al. (2003). External iliac artery endofibrosis: a new possible predisposing factor. J Vasc Surg., 38:180-182. DOI: 10.1016/S0741-5214(03)00123-X
Schep G, Kaandorp DW, Bender MHM, et al. (2002a). Excessive length of iliac arteries in athletes with flow limitations measured by magnetic resonance angiography. Med Sci Sports Exerc., 34:385-393.
Schep G, Bender MHM, van de Tempel G, Wijn PFF, de Vries WR, Eikelboom BC. (2002b). Detection and treatment of claudication due to functional iliac obstruction in top endurance athletes: a prospective study. Lancet, 359:466-473.
Schep G, Bender MHM, Schmikli SL, et al. (2002c). Recognising vascular causes of leg complaints in endurance athletes. Part 2: The value of patient history, physical examination, cycling exercise test and echo-doppler examination. Int J Sports Med., 23:322-328.
Sharifi M, Snyder R, Sharifi I, White E. (2024). Long-term outcome of percutaneous endovascular stenting in external iliac artery endofibrosis. Vascular Medicine, 29(3):256-264. DOI: 10.1177/1358863X241227476
van der Walt A, van Resnburg J, Fletcher L, Grant CC, van der Walt AJ. (2014). Non-traumatic injury profile of amateur cyclists. S Afr SM., 26(4):119-122. DOI: 10.7196/SAJSM.555
van Hooff M, Colenbrander FFC, Bender MHM, Savelberg HHHCM, Scheltinga MR, Schep G. (2023). Short- and long-term outcomes after endarterectomy with autologous patching in endurance athletes with iliac artery endofibrosis. J Vasc Surg., 78:514-524.
Venstermans C, Gielen JL, Salgado R, Bouquillon P, Lauwers J. (2009). Endofibrosis of the external iliac artery. JBR-BTR., 92:184-185.
Veraldi GM, Macri M, Criscenti P, Scorsone L, Zingaretti CC, et. al., (2015). Arterial endofibrosis in professional cyclists. G Chir. 36(6):267-271. DOI: 10.11138/gchir/2015.36.6.267
Vink A, Bender MH, Schep G, et al., (2008). Histopathological comparison between endofibrosis of the high performance cyclist and atherosclerosis in the external iliac artery. J Vasc Surg. 48:1458-63. DOI: 10.1016/j.jvs.2008.07.057
Weiss BD. (1985). Nontraumatic injuries in amateur long distance bicyclists. Am J Sports Med., 13:187-192.
White C. (2007). Intermittent claudication. N Engl J Med., 356:1241-50.
Wilson TD, Revesz E, Podbielski FJ, Blecha MJ. (2010). External iliac artery dissection secondary to endofibrosis in a cyclist. J Vasc Surg., 52:219-221. DOI: 10.1016/j.jvs.2010.02.259
Wijesinghe LD, Coughlin PA, Robertson I, Kessel D, Kent PJ, Kester RC. (2001). Cyclist’s iliac syndrome: temporary relief by balloon angioplasty. Br J Sports Med., 35:70–71.
Wu T, Olcott C, Lee JT. (2016). Operative results of iliac artery endofibrosis in high-performance athletes. J Vasc Surg., 64(2):P551.
Published
How to Cite
Issue
Section
Copyright (c) 2026 Journal of Science and Cycling

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Authors contributing to Journal of Science and Cycling agree to publish their articles under a Creative Commons CC BY-NC-ND license, allowing third parties to copy and redistribute the material in any medium or format, and to remix, transform, and build upon the material, for any purpose, even commercially, under the condition that appropriate credit is given, that a link to the license is provided, and that you indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
Authors retain copyright of their work, with first publication rights granted to Cycling Research Center.


